Scientists report chemotherapy cocktail may cause adult women to grow new egg cells

Wednesday, December 7, 2016

Chemotherapy is usually associated with a collection of side effects ranging from digestive problems to hair loss, but a study published this week in Human Reproduction demonstrated that female cancer patients may find they have something in common with much younger women in one specific area — their ovaries.

Scientists from the University of Edinburgh examined donated ovarian tissue from fourteen female cancer patients, most of whom had Hodgkin lymphoma, and compared it to tissue from healthy women. They found the samples from women who had been treated with a specific chemotherapeutic regimen known as ABVD not only contained greater numbers of dormant ova — egg cells — than those from women treated with harsher regimens but also more than samples from healthy women. ABVD is named for combining several drugs known as adriamycin, bleomycin, vinblastine, and dacarbazine.

These reproductive cells were not merely more plentiful in ABVD patients. They also appeared immature, “new” in the words of lead researcher Evelyn Telfer. This challenges the conventional belief that girls are born with all the ova they will ever have and the numbers can only go down as the cells are either used up by the reproductive cycle or succumb to damage or natural aging. However, further research is needed to confirm this. The study covered relatively few patients by scientific standards, and David Albertini of the Center for Human Reproduction in New York has suggested the cells may not actually be freshly grown. Instead, they may have always been there and were merely rendered more detectable by ABVD treatment.

The ability to grow new egg cells may have significant implications for women in Western societies, many of whom postpone childbearing to establish careers, sometimes into their late thirties or forties. However, Telfer warns against making use of these findings too soon: “There’s so much we don’t know about the ovary. We have to be very cautious about jumping to clinical applications.”

The experiments had been discussed earlier this year at the annual conference of the European Society of Human Reproduction and Embryology.

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At least fifteen dead after stampede at Mali mosque

Friday, February 26, 2010

According to a government official, at least 26 people were killed in a stampede on Thursday at a historic mosque in the northwestern city of Timbuktu, Mali.

“There were 26 killed and 40 wounded,” Oumar Sangare, the Internal Ministry spokesman, told Reuters. However, other news agency reports put the death toll as low as fifteen.

An official, who requested to remain anonymous, said the accident could have begun as a result of renovation work on the Djingareyber mosque—which is made primarily of mud, and was built in the fourteenth century. Construction work blocked off some of the roads, and that could have been a factor in the incident. “The mosque is being renovated, financed by the Aga Khan, and the work is carried out by South African specialists,” the official told the Agence France-Presse (AFP) news agency.

“Because of these renovations, the passage on the north side of the mosque is closed off. On that side, to get through, the faithful found an improvised alleyway. But the alley couldn’t take the number of people using it. So there was a stampede. Somebody shouted ‘someone has died’ and panic took over,” the same official went on to say.

Others have remarked that rescue services responded “very quickly” to the stampede, and helped the “many injured.”

The Xinhua news agency reports the stampede started when an elderly woman fell in one of the town streets near the city’s main mosque, where a sermon was being conducted in front of a large crowd; a passersby then rushed to assist the woman, apparently disrupting the crowd’s movement and causing the stampede.

“People were circling the mosque, a ritual at each Mouloud [the observance of the Prophet Mohammed’s birthday] and there was a huge crowd build up,” commented Mohamed Bandjougou, one of the witnesses to the event, to AFP by telephone. “There were at least fifteen dead. The bodies were taken to the morgue.”

Authorities warned the number of injured may actually be higher than reported, saying that “we cannot rule out the fact that the number of those injured will increase because some of them are still hiding in their homes instead of coming to the hospital.” A hospital source commented that some of the people hurt were in critical condition, and needed to be evacuated to the capital, Bamako, as soon as possible.

The mosque’s imam, who gave his name as Asseyuti, commented on the incident. “We’re in mourning. What happened is a real trauma. We accept the will of God. He gives us life, he takes it away,” he said.

According to an official statement, Malian president Amandou Toumani Toure is traveling to Timbuktu from Bamako in light of the stampede.

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Get Your Dentures Placed By The Best Dentist In Reading, Pa}

Get Your Dentures Placed By The Best Dentist In Reading, Pa

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Affordable Dental SolutionsVisiting a dental clinic is the best way out to get rid of the issues related to your oral hygiene. Many people are often facing the problem of missing teeth and looking for effective measures. In the past times, there were no complete treatment for missing teeth, but now dentures have been introduced as an optimal solution. You can easily get yourself treated with dentures under the supervision of the best dentist in Reading, PA.

No matter how bad the condition is, dentists have the solution for all dental conditions. Hence, you no more have to bear the toothaches and worst dental situations. To treat the same, many dentists have come up with dental dentures. Dental dentures are the appliances that can be removed easily and used as a replacement for missing teeth. The sun will help restore your beautiful smile. A denture is an effective, easily removable replacement for missing teeth as well as for surrounding tissues. There are mainly two types of dentures available, such as partial and complete dentures. Every dentist in Reading, PA is educated enough to undertake such tasks.

[youtube]http://www.youtube.com/watch?v=6oEefhBXJOU[/youtube]

Partial dentures are usually used when some of the teeth are missing. On the other hand, complete dentures are required when all teeth are missing. Partial dentures are very effective and can be used when one or more teeth remain neutral in the lower or upper jaw. It basically consists of replacement teeth that is attached to a gum-colored plastic base, which is connected by using a metal framework to hold the denture in the mouth. A fixed bridge is used to replace one or more teeth by using crowns on the teeth and attaching artificial made teeth to them.

Afterwards, the “bridge” is cemented into place. This will not only occupy the empty space, but also gives you a confidence to smile again. There are many benefits of using partial dentures. It also prevents other teeth from changing their actual position. The dentures are removable and looks more natural. If you have one or more missing teeth, then you need to consult a dentist in Reading, PA

. Complete dentures make a perfect choice for those having all teeth missing. Complete dentures can be either “immediately” or “conventional.”

The immediate dentures are made in advance and can be placed in the short time span. They are positioned in the mouth as soon as the teeth are removed. Irrespective of the type of dentures, all you need to do is to consult an experienced dentist in your treatment. The dentures are usually made of plastic or metal base. There are many dentists available on the web offering a wide variety of dental services. Make sure to choose the one that best suits your needs. You can even ask your family or friends for their recommendations. Do not forget to read the testimonials posted by the previous clients to get an idea about their services.

To get more information about the dental dentures, you may search over the internet.Affordable Dental Solutions

is a dental care clinic in reading PA where highly qualified dentists offer dental treatment to let you achieve optimum dental health.

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Scottish artist Alan Davie dies at age 93

Tuesday, April 8, 2014

The death of Scottish artist Alan Davie was announced on Sunday. Davie, 93, was known for his colourful abstract paintings.

Davie’s career also saw turns as a jeweler, a jazz musician, a lecturer, and a poet. Born in Grangemouth, near Falkirk, in 1920, he studied painting from 1938 to 40 at Edinburgh College of Art.

It’s an urge, an intensity, a kind of sexual need

His father was a teacher who dabbled in art and his mother’s family was musically inclined. Upon seeing Coleman Hawkins performing in a music shop in Edinburgh, Davie borrowed £600 from his father to buy himself a saxophone. After serving in the Second World War, at which time he wrote much poetry later transcribed by his father, Davie toured with Scottish jazz bands.

Davie’s work was admired by the likes of Jackson Pollock, Mark Rothko and David Hockney. Davie himself collected non-Western art and liked tattoos, graffiti, and ‘outsider art’. His final interview before death, with The Telegraph, gave an insight into how he viewed art: “It’s an urge, an intensity, a kind of sexual need[…] something I do from an inner compulsion, that has to come out.”

He initially avoided painting as a career at all, then spent several years earning money by other means whilst his paintings failed to sell. His exhibitions in the late 1950s, however, were highly successful and launched his career. He was in the habit of choosing titles for his art only after completion.

Despite a strong presence owing to his lengthy red beard and off-beat humour, he was shy; his international fame waned. Recent years have seen a revival of interest with price increases for his early art. London alone is host to three exhibitions this month including at the Tate.

Tate Britain calls Davie “one of the first British artists after the war to develop an expressive form of abstraction” producing “kaleidoscopic canvases[…] that the artist relates to his love of jazz”.

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Charles Lazarus, founder of US-based toy retail giant Toys ‘R’ Us, dies at 94

Saturday, March 24, 2018

On Thursday, Charles Lazarus, the founder of United States toy retailer Toys “R” Us, died in Manhattan, New York, New York of respiratory failure. He was 94. His death came a week after Toys “R” Us announced that all of the stores were closing.

Toys “R” Us issued a statement in which they said, “There have been many sad moments for Toys “R” Us in recent weeks, and none more heartbreaking than today’s news about the passing of our beloved founder, Charles Lazarus. He visited us in New Jersey just last year and we will forever be grateful for his positive energy, passion for the customer and love for children everywhere. Our thoughts and prayers are with Charles’ family and loved ones.”

Michael Goldstein, who was a close friend and former Toys “R” Us chairman, said: “He was the father of the toy business. He knew the toys and loved the toys and loved the kids who would shop in the stores. His face lit up when he watched kids playing with toys.” In a phone interview Goldstein said that Charles Lazarus died in Manhattan.

Lazarus no longer held a stake in the chain, CNN reported. Lazarus took over his father’s bicycle repair shop in 1948 at the age of 25 and changed it to baby furniture. He opened the first Toys “R” Us store in 1957. Lazarus had remained its CEO until 1994.

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U.S. outlaws online gambling

Saturday, October 14, 2006

Over the weekend, millions of Americans faced the new ban of online gambling.

The legislation was attached by Rep. Bill Frist to the Port Security bill.

Many of the public companies that offer online gambling have been quick to react and give their outlooks on the legislature. Party Gaming and 888 among others have said that they will shut down all U.S. operations if President Bush signs the bill into law. This sent online gambling stocks tumbling with Party Gaming leading the way with a 55% decrease in market value.

The people involved are awaiting to see what happens over the next few weeks.

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Buildmate Crusher Plants Machine Manufacturers

set to make the advancement business in India progressively splendid.

Current Construction Machines Crusher Suppliers and Crusher Machinery suppliers are envisioning higher business affirmation. As demonstrated by industry improvement, the intrigue is foreseen to create 15-20% during the present and coming years. This inconceivable intrigue would be driven by the association’s need for the wrangled item offering. Regardless, plants are believed to experience a contracting demand to organize at any rate for a long time. The creators are tackling exhibiting frameworks, maintained by thing offering, to meet the creating need for extreme tests for wrangled units, while the technique is being improved to offset declining offers of pursued units.

The continuous decision of the Supreme Court, denying the preclusion on iron mineral mining in Goa setting 20 million tons on mining has conveyed cheers to the camp of beating plant makers, reeling under the deferred sink of iron metal mining developing out of the blacklist. Makers are in like manner glad on the top of the line augmentation of the Steel Authority of India. The PSU behemoth has starting late dispatched its new shoot warmer in its Eastern India office, accordingly requiring updated treatment of iron mineral. The coordinated summit of a uber steel plant in Odisha by Tata Steel and that of Bhushan steel close by a persistent organized expansion of scores of discretionary steel plants in West Bengal and Jharkhand are furthermore the clarifications behind the improved business thought. Progression of additional cutting-edge avenues stretches out in the North Eastern bit of the country, required to be worked through affecting entering and Stone beating is an extra reason behind improved business evaluation both for the Crushing plant and plant customers.

On creating business part designs stone Crusher Machine Suppliers in India, ” customers are right now scanning for a complete course of action from the equipment producers. The enthusiasm for high-quality courses of action is furthermore extending, be that as it may, the standard modules of plants are so far the most well known. With Buildmate Crusher Plants Machine Manufacturers and Suppliers Products extent of equipment support, we offer our customers a hard and fast course of action groups including beating. These packs can be offered either on wheel plants, estimated plants or as unit apparatus and articulation.

Nevertheless, the immense intrigue figures, foreseen by Stone Crusher Machine makers, addressing the wrangled portion are required to start from road improvement and moreover from focus structure adventures which are hydropower adventures. Thronging of the creating interest space by existing suppliers and moreover by various new specialists, over the scope of four years, including Indian and overall associations, on clear grounds would not be dismissed from contention factor. This is all around expected to carry more cutting-edge objectives and esteeming benefits and included help support for customers From Crushing Plant Manufacturers.

The increasing expense of rough materials is a significant snag standing up to the staggering and screening industry. Setting up a staggering unit remembers huge costs and detachment of unrefined material for time just adds to the cost. Another test going up against this industry incorporates serious government rules. Since characteristic issues remembering quarries for various states are yet to be out and out settled, as a rule, the solicitation will keep on the pain. In particular, crushing units that are working without the “official consent” from the Pollution Control Boards(PCB) are in the veritable risk of being shut down. Additionally, there is a lack of capable and arranged individuals because of which the business enrolls a gigantic number of incompetent ordinary specialists to do the exercises of mining stone crusher.

Buildmate is a front line supplier and maker of this eco-pleasing and viable Crusher Machine Suppliers in India, set to make the advancement business in India progressively splendid.

Hyperledger: The Best Blockchain Framework For The Healthcare Industry

Thursday, May 5, 2022

Category:Technology

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Sweden’s Crown Princess marries long-time boyfriend

Monday, June 21, 2010

Sweden’s first royal wedding since 1976 took place Saturday when Crown Princess Victoria, 32, married her long-time boyfriend and former personal trainer, Daniel Westling, 36. The ceremony took place at Stockholm Cathedral.

Over 1,200 guests, including many rulers, politicians, royals and other dignitaries from across the world, attended the wedding, which cost an estimated 20 million Swedish kronor. Victoria wore a wedding dress with five-metre long train designed by Pär Engsheden. She wore the same crown that her mother, Queen Silvia, wore on her wedding day 34 years previously, also on June 19. Victoria’s father, King Carl XVI Gustaf, walked Victoria down the aisle, which was deemed untraditional by many. In Sweden, the bride and groom usually walk down the aisle together, emphasising the country’s views on equality. Victoria met with Daniel half-way to the altar, where they exchanged brief kisses, and, to the sounds of the wedding march, made their way to the the silver altar. She was followed by ten bridesmaids. The couple both had tears in their eyes as they said their vows, and apart from fumbling when they exchanged rings, the ceremony went smoothly.

Following the ceremony, the couple headed a fast-paced procession through central Stockholm on a horse-drawn carriage, flanked by police and security. Up to 500,000 people are thought to have lined the streets. They then boarded the Vasaorden, the same royal barge Victoria’s parents used in their wedding, and traveled through Stockholm’s waters, accompanied by flyover of 18 fighter jets near the end of the procession. A wedding banquet followed in the in the Hall of State of the Royal Palace.

Controversy has surrounded the engagement and wedding between the Crown Princess and Westling, a “commoner”. Victoria met Westling as she was recovering from bulemia in 2002. He owned a chain of gymnasiums and was brought in to help bring Victoria back to full health. Westling was raised in a middle-class family in Ockelbo, in central Sweden. His father managed a social services centre, and his mother worked in a post office. When the relationship was made public, Westling was mocked as an outsider and the king was reportedly horrified at the thought of his daughter marrying a “commoner”, even though he did so when he married Silvia. Last year, Westling underwent transplant surgery for a congenital kidney disorder. The Swedish public have been assured that he will be able to have children and that his illness will not be passed on to his offspring.

Westling underwent years of training to prepare for his new role in the royal family, including lessons in etiquette, elocution, and multi-lingual small talk; and a makeover that saw his hair being cropped short, and his plain-looking glasses and clothes being replaced by designer-wear.

Upon marrying the Crown Princess, Westling took his wife’s ducal title and is granted the style “His Royal Highness”. He is now known as HRH Prince Daniel, Duke of Västergötland. He also has his own coat-of-arms and monogram. When Victoria assumes the throne and becomes Queen, Daniel will not become King, but assume a supportive role, similar to that of Prince Phillip, the husband of the United Kingdom’s Queen Elizabeth II.

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Commonwealth Bank of Australia CEO apologies for financial planning scandal

Thursday, July 3, 2014

Ian Narev, the CEO of the Commonwealth Bank of Australia, this morning “unreservedly” apologised to clients who lost money in a scandal involving the bank’s financial planning services arm.

Last week, a Senate enquiry found financial advisers from the Commonwealth Bank had made high-risk investments of clients’ money without the clients’ permission, resulting in hundreds of millions of dollars lost. The Senate enquiry called for a Royal Commission into the bank, and the Australian Securities and Investments Commission (ASIC).

Mr Narev stated the bank’s performance in providing financial advice was “unacceptable”, and the bank was launching a scheme to compensate clients who lost money due to the planners’ actions.

In a statement Mr Narev said, “Poor advice provided by some of our advisers between 2003 and 2012 caused financial loss and distress and I am truly sorry for that. […] There have been changes in management, structure and culture. We have also invested in new systems, implemented new processes, enhanced adviser supervision and improved training.”

An investigation by Fairfax Media instigated the Senate inquiry into the Commonwealth Bank’s financial planning division and ASIC.

Whistleblower Jeff Morris, who reported the misconduct of the bank to ASIC six years ago, said in an article for The Sydney Morning Herald that neither the bank nor ASIC should be in control of the compensation program.

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