Dozens dead in Connecticut school shooting

 Note — August 24, 2015 This article is insufficiently clear on one detail, namely that one victim (the gunman’s mother) was shot and killed in a separate location. The toll of 28 includes her and the gunman. 

Friday, December 14, 2012

Before turning the gun on himself, a 20-year-old male opened fire at Sandy Hook Elementary School in Newtown, Connecticut, killing 28 people, 20 of them children ranging from five to ten years old. Approximately 600 students were inside the school.

The New York Post identifies the shooter as 20-year-old Adam Lanza. He was reported to be in possession of a .223-caliber assault rifle and two hand guns when he opened fire inside the school. His motives are not yet clear, but reports say his mother Nancy, who was also killed, may have been the target. She was a teacher of a kindergarten class at the school. Adam’s brother Ryan, who was initially reported to be the shooter, is also in police custody.

United States president Barack Obama spoke in a televised address saying, “The majority of those who died today were children — beautiful little kids between the ages of 5 and 10 years old. They had their entire lives ahead of them — birthdays, graduations, weddings, kids of their own. Among the fallen were also teachers — men and women who devoted their lives to helping our children fulfill their dreams.

“So our hearts are broken today — for the parents and grandparents, sisters and brothers of these little children, and for the families of the adults who were lost. Our hearts are broken for the parents of the survivors as well, for as blessed as they are to have their children home tonight, they know that their children’s innocence has been torn away from them too early, and there are no words that will ease their pain.”

A hospital near the school, in Danbury, Connecticut, is currently on lock down. According to The New York Times and Danbury Hospital’s Facebook page, the hospital is treating three of the shooting victims.

Retrieved from “https://en.wikinews.org/w/index.php?title=Dozens_dead_in_Connecticut_school_shooting&oldid=3806899”

Asbestos controversy aboard Scientology ship Freewinds

Friday, May 16, 2008

Controversy has arisen over the reported presence of blue asbestos on the MV Freewinds, a cruise ship owned by the Church of Scientology. According to the Saint Martin newspaper The Daily Herald and the shipping news journal Lloyd’s List, the Freewinds was sealed in April and local public health officials on the Caribbean island of Curaçao where the ship is docked began an investigation into the presence of asbestos dust on the ship. Former Scientologist Lawrence Woodcraft supervised work on the ship in 1987, and attested to the presence of blue asbestos on the Freewinds in an affidavit posted to the Internet in 2001. Woodcraft, a licensed architect by profession, gave a statement to Wikinews and commented on the recent events.

According to The Daily Herald, the Freewinds was in the process of being renovated by the Curaçao Drydock Company. The article states that samples taken from paneling in the ship were sent to the Netherlands, where an analysis revealed that they “contained significant levels of blue asbestos”. An employee of the Curaçao Drydock Company told Radar Online in an April 30 article that the Freewinds has been docked and sealed, and confirmed that an article about asbestos ran in the local paper.

Lloyd’s List reported that work on the interior of the Freewinds was suspended on April 27 after health inspectors found traces of blue asbestos on the ship. According to Lloyd’s List, Frank Esser, Curaçao Drydock Company’s interim director, joined Curaçao’s head of the department of labor affairs Christiene van der Biezen along with the head of the local health department Tico Ras and two inspectors in an April 25 inspection of the ship. “We are sending someone so that they can tell us what happened, where it came from, since when it has been there,” said Panama Maritime Authority’s director of merchant marine Alfonso Castillero in a statement to Lloyd’s List.

The Church of Scientology purchased the ship, then known as the Bohème, in 1987, through an organization called Flag Ship Trust. After being renovated and refitted, it was put into service in June 1988. The ship is used by the Church of Scientology for advanced Scientology training in “Operating Thetan” levels, as well as for spiritual retreats for its members. Curaçao has been the ship’s homeport since it was purchased by the Church of Scientology.

According to his 2001 statement, Lawrence Woodcraft had been an architect in London, England since 1975, and joined Scientology’s elite “Sea Organization” (Sea Org) in 1986. He wrote that he was asked by the Sea Org to work on the Freewinds in 1987, and during his work on the ship “noticed a powdery blue fibrous substance approximately 1 ½” thick between the paint and the steel wall,” which he believed to be asbestos. He also discovered what he thought was blue asbestos in other parts of the ship, and reported his findings to Church of Scientology executives. Woodcraft discussed his experiences in a 2001 interview published online by the Lisa McPherson Trust, a now-defunct organization which was critical of the Church of Scientology.

The Freewinds regularly inspects the air quality on board and always meets or exceeds US standards.

Church of Scientology spokeswoman Karin Pouw responded to Radar Online about the asbestos reports, in an email published in an article in Radar on May 1. “The Freewinds regularly inspects the air quality on board and always meets or exceeds US standards,” said Pouw. She stated that two inspections performed in April “confirmed that the air quality is safe,” and asserted that the inspections revealed the Freewinds satisfies standards set by the United States Occupational Safety and Health Administration and the U.S. Clean Air Act.

Pouw told Radar that “The Freewinds will be completing its refit on schedule.” The Church of Scientology-affiliated organization Citizens Commission on Human Rights (CCHR) had been planning a cruise aboard the Freewinds scheduled for May 8, but according to Radar an individual who called the booking number for the cruise received a message that the cruise had been delayed due to ongoing work on the ship. Citing an article in the Netherlands Antilles newspaper Amigoe, Radar reported on May 6 that a team from the United States and supervised by an independent bureau from the Netherlands traveled to Curaçao in order to remove asbestos from the Freewinds.

…if the Church of Scientology claims to have removed the blue asbestos, I just don’t see how, it’s everywhere. You would first have to remove all the pipes, plumbing, a/c ducts, electrical wiring etc. etc. just a maze of stuff.

“I stand by everything I wrote in my 2001 affidavit,” said Lawrence Woodcraft in an exclusive statement given to Wikinews. Woodcraft went on to state: “I would also comment that if the Church of Scientology claims to have removed the blue asbestos, I just don’t see how, it’s everywhere. You would first have to remove all the pipes, plumbing, a/c ducts, electrical wiring etc. etc. just a maze of stuff. Also panelling as well, basically strip the ship back to a steel hull. Also blue asbestos is sprayed onto the outer walls and then covered in paint. It’s in every nook and cranny.”

Many Scientologist celebrities have spent time aboard the Freewinds, including Tom Cruise, Katie Holmes, John Travolta, Kelly Preston, Chick Corea, Lisa Marie Presley, Catherine Bell, Kate Ceberano, and Juliette Lewis. Now magazine reported that Tom Cruise has been urged to seek medical attention regarding potential asbestos exposure, however a representative for Cruise stated he has “absolutely no knowledge” of the recent asbestos controversy. Cruise, Holmes, Travolta and Preston have celebrated birthdays and other events on the Freewinds.

There is not now and never has been a situation of asbestos exposure on the Freewinds.

In a May 15 statement to the United Kingdom daily newspaper Metro, a representative for the Church of Scientology said that “There is not now and never has been a situation of asbestos exposure on the Freewinds.” The Asbestos and Mesothelioma Center notes that agencies have recommended anyone who has spent time on the Freewinds consult with their physician to determine if possible asbestos exposure may have affected their health.

Raw blue asbestos is the most hazardous form of asbestos, and has been banned in the United Kingdom since 1970. Blue asbestos fibers are very narrow and thus easily inhaled, and are a major cause of mesothelioma. Mesothelioma is a form of cancer which can develop in the lining of the lungs and chest cavity, the lining of the abdominal cavity, or the pericardium sac surrounding the heart. The cancer is incurable, and can manifest over 40 years after the initial exposure to asbestos.

“This is the most dangerous type of asbestos because the fibres are smaller than the white asbestos and can penetrate the lung more easily,” said toxicologist Dr. Chris Coggins in a statement published in OK! Magazine. Dr. Coggins went on to note that “Once diagnosed with mesothelioma, the victim has six months to a year to live. It gradually reduces lung function until the victim is no longer able to breathe and dies.”

Retrieved from “https://en.wikinews.org/w/index.php?title=Asbestos_controversy_aboard_Scientology_ship_Freewinds&oldid=4647051”

Penis Pain How To Tell If It S A Penis Fracture

Penis Pain How to Tell if it s a Penis Fracture

by

John Dugan

The term penis fracture is a cringe-inducing one no man wants to even think about a broken penis, never mind experience it. In fact, it doesn t even sound possible how can the penis be fractured when it doesn t have any bones? Unfortunately, though, it is true the penis can break and knowing when to get help can make all the difference between a short-term inconvenience and a lifetime of discomfort and impaired performance. Plus, since avoiding a penis fracture in the first place is the best solution, penis heath remedies and tips for preventing a broken penis are discussed here.

Penis fractures how and why

To understand what is meant by a penis fracture, it is necessary to be aware of the underlying anatomy of the penis. Essentially, the shaft of the penis consists of a spongy tissue known as the corprora cavernosa the part of the penis that becomes filled with blood during an erection. This tissue is surrounded by a fibrous membrane called the tunica albuginea, which holds it in place and gives it its shape.

If the penis is bent or buckled abruptly during sex or whatever this outer membrane can rupture, resulting in sudden, severe pain that may be accompanied by a loud, popping noise. Penis fractures are most common during sexual activity where the woman is on top and comes down suddenly at an unfortunate angle, or when the man thrusts and hits the woman s pubic bone.

[youtube]http://www.youtube.com/watch?v=iDatdjvoMp4[/youtube]

An interesting side note on this issue, according to Dr. Andrew Kramer, a urologist at the University of Maryland Medical Center, is that in many cases, penis fractures appear to occur during extramarital affairs or in places besides the bedroom. There is some logic to this idea, since doing it in an unauthorized location or with an unauthorized person is likely to create a more heated and frantic atmosphere.

Treating a broken penis

Regardless of how the penis is broken, when a fracture occurs, it should be considered a medical emergency. Surgical correction is generally necessary to prevent long-term problems. Unfortunately (and possibly because of the circumstances mentioned above), many men are reluctant to seek medical attention due to embarrassment or the fear of spousal fury and hope that the problem will resolve on its own.

Implications of a broken penis

Unfortunately, leaving a broken penis to heal on its own can lead to several complications. Permanent deformity, as well as ongoing pain, are the most obvious of these, and leaving a fracture untreated can lead to loss of function. But even a penis that appears to heal normally may present with problems later on. Scar tissue may develop as part of the healing process. This scar tissue does not expand in the same way as the surrounding membrane, which can cause mild to severe bending during an erection. This, in turn, can lead to painful intercourse or even impotence.

Preventing penis fractures

Clearly, prevention in this case is the best medicine. For men who are prone to acrobatics in the bedroom, the best advice is to keep the penis moisturized, use a lubricant, and really, just be as careful as possible. Supporting healthy skin and connective tissue by keeping the manhood well-nourished with the rejuvenating vitamins and minerals found in a high-quality penis health cr me (most health professionals recommend Man1 Man Oil) can help to keep the penis moisturized and supple and reduce the risk of developing scar tissue related to chronic rough handling or sudden trauma. A health cr me that is applied directly to the penis will be absorbed directly into the penis skin for maximum benefit.

For additional information on most common

penis health issues

, tips on improving penis sensitivity, and what to do to maintain a healthy penis, visit:

penishealth101.com

. John Dugan is a professional writer who specializes in men’s health issues and is an ongoing contributing writer to numerous online web sites.

Article Source:

Penis Pain How to Tell if it s a Penis Fracture

Iran’s morality police crack down on un-Islamic dress

Wednesday, April 25, 2007

The Iranian police forces have faced criticism from Ayatollah Hashemi Shahrudi, the head of the judiciary who was appointed by Grand Ayatollah Ali Khamenei, for their re-invigorated campaign to do away with un-Islamic dress.

Ayatollah Shahroudi proclaimed, “Tough measures on social problems will backfire and have counter-productive effects.” Others have, of course, made it clear that un-Islamic dress can lead to moral corruption, engender innumerable vices, and hurt the Islamic character of the nation.

Some believe that no one had any issue with the creation of an Islamic atmosphere. The core of the matter revolves around the implementation of the Islamic dress code; additionally, heavy-handed measures should be shunned. For instance, Mehdi Ahmadi, information head of Tehran’s police, told Al Jazeera: “Some citizens may complain about the way the law is being enforced but they all agree with the plan itself.”

According to one student, “You simply can’t tell people what to wear. They don’t understand that use of force only brings hatred towards them, not love.” Nevertheless, Hojatoll-Islam Mostafa Pour-Mohammadi, Iran’s interior minister who is in charge of policing, prognosticated positive feedback from the populace when he said, “People are unhappy with the social and moral status of the society. They expect that the fight against social insecurity be properly implemented.” Thus, Hujjat al-Islam Pour-Mohammadi re-iterated the necessity of proper implementation and methodology towards the restoration of morality in the Islamic Republic. Islamic officials and religious people affirm that this is indispensable to promote righteousness, curb sin, and bring open sinners to justice.

Following the Islamic Revolution in 1979, hijab became mandatory in Iran for every woman including foreigners after over 98% of citizens voted for an Islamic government. Women may face caning up to 74 strokes for failing to observe hijab. In this recent crackdown, the authorities have arrested many citizens throughout the country. Not only have women been taken into custody for their hair being uncovered on their foreheads and tight clothes that show body shapes, For men they need to cover from knee to their waist as according to Sharia. Even a foreign journalist was detained because the photograph on her press card was indecent.

It has not been clear whence the directive for the re-newed clampdown emanated. Some have blamed Mahmoud Ahmadinejad while Gholam Hossein Elham, the government spokesman, stated to reporters, “The police work as agents of the judiciary to confront crimes. The government as an executive body does not interfere in the affairs of the judiciary.” The following pre-election speech seems to corroborate this latter statement:

In reality, is the problem of our people the shape of the hair of our children? Let our children arrange their hair any way they wish. It doesn’t concern me and you. Let you and me overhaul the basic problems of the nation. The government should fix the economy of the nation and improve its atmosphere…[It should] better psychological security and support the people. People have variegated tastes. As if now the arch obstacle of our nation is the arrangement of our kids’ hair and the government disallowing them <He chuckles>. Is this the government’s responsibility? Is this the people’s merit? In actuality, this is the denigration of our people. Why do you underestimate and belittle the people? It is the real issue of our nation that one of our daughters donned a certain dress? Is this the issue of our nation and the problem of our nation?
Retrieved from “https://en.wikinews.org/w/index.php?title=Iran%27s_morality_police_crack_down_on_un-Islamic_dress&oldid=4558895”

Inquiry finds proper maintenance might have prevented 2009 North Sea helicopter disaster

Sunday, March 16, 2014

A Fatal Accident Inquiry (FAI) ruled on Thursday a helicopter crash into the North Sea might have been prevented had proper maintenance procedures been followed. All sixteen on board died when the aircraft went down off the Scottish coast.

After a hearing in Aberdeen, Sheriff Principal Derek Pyle found Bond Offshore Helicopters failed to remove a component after a metal shard was found. The shard suggested spalling, or the shedding of metal particles in the aircraft’s gearbox. “The size and shape of the particle found […] were consistent with an advanced stage of classic spalling” according to the inquiry’s findings.

A week before the crash Bond mulled partially replacing the gearbox. The aircraft went down after the gearbox failed in flight. Pyle found a failure in communication between Bond and helicopter manufacturer Eurocopter had led to the decision not to replace the gearbox.

The routine flight was taking oil workers back to Aberdeen from the Miller offshore oil platform, owned by BP. The aircraft radioed air traffic control to inform they were twenty minutes from Aberdeen Airport but six seconds later was confronted with an oil warning light and grinding sounds. The crew declared an emergency but the main rotor broke free, which in turn smashed through the tail leaving the aircraft to plunge into the sea. The aircraft crashed within twenty seconds of the first sign of trouble.

The inquiry is surrounded by controversy owing to the five-year gap between accident and findings, and the decision by Crown Office not to prosecute over the crash. “For a criminal prosecution to have taken place, the Crown would have to prove its case beyond reasonable doubt” a Crown Office statement said on Thursday. “The Sheriff Principal makes clear that a reasonable doubt remained over the technical cause of the crash”.

Although the Air Accidents Investigation Branch (AAIB) and Sheriff Pyle found a catastrophic gearbox failure triggered the crash, the exact cause of the failure was never conclusively decided. After hearing expert evidence Pyle found the balance of probabilities pointed to spalling, but could not rule out a manufacturing defect.

The inquiry’s findings note “that it would be an extraordinary coincidence if the failure properly to carry out inspection and maintenance of the helicopter’s gearbox was not causative of a catastrophic failure of the same within a matter of days. But, as the evidence made clear, such a coincidence was indeed a possibility.” Pyle’s report added “the small piece of the helicopter which would have proved the matter beyond any doubt [has] not been recovered from the seabed”.

We have always accepted that we made mistakes through honest confusion over telephone calls and emails

Bond have released a statement noting “We have always accepted that we made mistakes through honest confusion over telephone calls and emails.” Sheriff Pyle found Bond’s employees “tried to carry out their jobs as diligently as they could. All of them impressed me as engineers who well understood the vital importance of their role in ensuring […] safety”. He also found staff were well-trained and resourced, echoing findings by the AAIB and the Civil Aviation Authority.

Pyle noted Bond readily accepted they should have properly followed the maintenance manual and normally did, but “on one occasion, that fundamental rule was broken” and the crash was likely a result. Bond, Eurocopter, and investigators all gave evidence.

Trade unions and victims’ families, however, have slammed the decision not to prosecute. While welcoming the FAI’s conclusions, victims’ lawyer Tom Marshall said the families wanted to review the decision not to prosecute with the Lord Advocate, and are also seeking a broader public inquiry. Audrey Wood, whose son Stuart died in the disaster, said “How [Crown Office] arrived at that decision [not prosecuting] will haunt us, as not only did we hear of multiple breaches of health and safety, but the decision was also made without all the evidence being present, as vital witness statements had not been given”.

Wood said there were multiple breaches of health and safety law that could be prosecuted. Crown Office’s statement counters “evidence presented during the FAI has not altered the insufficiency of evidence, therefore the decision not to hold criminal proceedings remains the correct one”. Unite union branded their decision a “travesty of justice”.

Politicians have criticised the five-year delay holding the FAI, as has Scottish Trades Union Congress general secretary Grahame Smith who said “It is vitally important that lessons are learned at the earliest opportunity following tragedies where lives are lost”. Sheriff Pyle himself concluded “what can, I think, very properly be said is that nearly five years [delay] is on any view far too long and that we all have a responsibility for that. […] everyone concerned in future fatal accidents involving aircraft of whatever kind should do much better.”

Labour have called for new FAI rules; MSP Patricia Ferguson has put a bill before parliament; the Scottish Government says Sheriff Pyle’s conclusions are being scrutinised. MSP Richard Baker said the victims’ families and North Sea oil workers, who routinely use helicopters, had waited “far too long” for the FAI to conclude. “FAIs should never be delayed so long again.”

Crown Office expressed sympathy with the families involved for the delay but blamed the complex nature of the investigation, and pointed out the AAIB, Civil Aviation Authority, and local police had all already conducted their own enquiries. The AAIB spent 30 months investigating.

Twelve victims were from Scotland, many of those from in and around Aberdeen where the six-week inquiry was held. Three more were from elsewhere in the UK and the last was a Latvian national. Half of the fourteen passengers and two crew died “instantaneously” and the rest died very shortly after impact with the sea from blunt force trauma, the inquiry found.

None survived long enough to drown, according to Sheriff Pyle. Nonetheless he noted “there was a poignant moment when a witness was being taken through the graph in the AAIB report which set out the timeline of the accident that I, if not others present, understood for the first time the true horror of what took place.”

Audrey Wood said “The length of wait for nearly five years has been intolerable for all the families and we, the families, feel let down by the system.” Bond’s statement this week says “We would like to express again our deep sorrow at the 16 lives lost. Bond Offshore hopes [the inquiry] brings a degree of closure to the families, friends and dependents of those who died in the tragedy of 2009.” The sheriff also noted the “courage” of victims’ families, who attended the full hearing.

Retrieved from “https://en.wikinews.org/w/index.php?title=Inquiry_finds_proper_maintenance_might_have_prevented_2009_North_Sea_helicopter_disaster&oldid=2499024”

“Woofstock” dog festival in Toronto, Ontario, Canada

Tuesday, June 12, 2007

North America’s largest outdoor dog festival came back to Toronto last weekend for its fifth year. It ran from the 9th of June to the 10th of June at Toronto’s historical St. Lawrence Market. A Wikinews reporter was there on Sunday to report on some of the events that happened on the last day.

The “Woofstock” dog festival attracted as many as 140,000 people with their dogs. The festival had tons of accessories, sold under tents, to buy for dogs; food, toys, designer clothes, and more. About 400 vendors and exhibitors were there to promote their products, which also gave private dog companies or groups a chance to show their new products. The local SPCA and some animal rescues were under tents answering questions from visitors. While walking, all visitors could see the CN Tower and other very tall buildings.

One of the local TV stations, Citytv, was there. They hosted a live event at the show which was broadcast on TV. People came up on the stage and asked questions regarding their dogs and the host and co-host answered them.

A man, who called himself the “Chalk Master”, drew two pictures on pavement with chalk. He did it for free but donations were welcome. One was a picture of a girl’s head beside a dog’s head, and another with a wolf.

“Hello Humans. I’ve been invited here to provide your eyeball(s), with some pretty colours. I don’t get paid as I work this weekend strictly for tips… so, if you like what you see please make a DONATION. If you don’t like it simply reach into the pocket of the person next to you and give me their money. CHALK MASTER.”

A contest called “Canada’s top dog” had its own tent with a professional photographer taking pictures of dogs behind a white screen; the winning photo is to be published on the cover of “Puppy and dog basics” magazine.

Large “Gourmet” dog bones were also served from a cart and table.

Next year’s festival is expected to be bigger and better with even more attractions.

Retrieved from “https://en.wikinews.org/w/index.php?title=%22Woofstock%22_dog_festival_in_Toronto,_Ontario,_Canada&oldid=724933”

How To Make Money Online ?

How to make money online?There are several ways to make money online, including online survey, searching for web, market trading, own website, write and publish ebook, affiliate marketing and etc.Making money with online survey is very popular nowadays because many company do a lot of research and recruit members to fill up the form , answer and test their product. You can earn money by filling up the form.Market trading, forex, is leveraging and can earn a lot , however there are risk involved and can loss your whole capital. Investing in stocks and currency are popular and you can do or trade with market platform that broker provided.If you are not proper trained, trade, you will be like gambler and loss all money. The most important thing is you need to set your profit limit, control your emotion and must have proven strategy. There is copy trader that you can copy trade,and you need to pay monthly fee, but i am not sure you will get the winning trade.Starting your own website is one of the way that you can get money online while you are sleeping or wherever you are.You can start learning how to create website and use domain and hosting which might cost you a bit. You might have a bit of struggling to get first visitor and there are plenty of ways to monetize your website.Review website is another source of income that you can get. Browsing website is paid job and you can be one of them, but you cannot get money if you do not review them.Write and Publish ebook is another source of passive income that you can get while you are on holiday. Kindle app is available on iphone, ipad, smartphone so the market for ebook is enormous. When you do ebook, the cover design is important because it will stand out before people read inside. You can ask readers to review at the end of kindle book, so it will show up and got higher results.Fiverr is source of place that you can earn money beacuse it is huge marketplace that people sell their small service including writing translating, social media posting , teaching music for all over the world. Review Music is the one that you can get money online as well, you can review artist and band and can get $US , however you need to build up your trust and you cannot get anything if you stop working.Selling education, it is one of the most popular ways that you can sell your expertise and become a online tutor and you can go around the world. You need to build trust and become popular.Freelancing is that you can write, manage facebook page or website and some kind of design you can make and earn while developing trust and experience.Network marketing or Multi-level marketing is business model that you can earn 2 ways by getting commission from products and recruiting members to become part of sale team . It become popular because of social media and many people get income from this.Affiliate Marketing is one of the thing that you can get money online. You need to register on a lot of website which has affiliate area and become member, after that you can start promoting your products and get passive income while you are sleeping. However, you must have a proven effective system that work for you and show you how to do it and can get residual income.

If you want to find out more, please check out the link below

Friendly from

lin lin

Ontario Votes 2007: Interview with Green Party candidate Brett McKenzie, London North Centre

Saturday, October 6, 2007

Brett McKenzie is running for the Green Party of Ontario in the Ontario provincial election, in the London North Centre riding. Wikinews’ Nick Moreau interviewed him regarding his values, his experience, and his campaign.

Stay tuned for further interviews; every candidate from every party is eligible, and will be contacted. Expect interviews from Liberals, Progressive Conservatives, New Democratic Party members, Ontario Greens, as well as members from the Family Coalition, Freedom, Communist, Libertarian, and Confederation of Regions parties, as well as independents.

Retrieved from “https://en.wikinews.org/w/index.php?title=Ontario_Votes_2007:_Interview_with_Green_Party_candidate_Brett_McKenzie,_London_North_Centre&oldid=704947”

Gene therapy trial for skin cancer cures two terminal patients

Friday, September 1, 2006

Results of gene therapy trials at the US National Cancer Institute, Bethesda to fight cancer published online yesterday by the scientific journal Science show some levels of success. However experts have warned that despite the promise more work is needed for this to become a viable cure.

Dr Stephen Rosenberg, who lead the research team, said “It’s important to emphasize this is a highly experimental treatment that’s still in the course of development.”

The team treated 17 terminal skin cancer patients with modified cells from their immune systems. The technique uses genetically modified white blood cells (more specifically T cells) to attack and kill the cancer cells. Of the 17 subjects only 2 were cured of the disease (an aggressive form of skin cancer called a melanoma which is usually fatal in advanced stages). Before the treatment, which lasted 18 months, the patients were only expected to live for up to 6 months. The remaining 15 patients were not affected by the treatment.

One of the successful patients was Mark Origer (53) from Wisconsin. He has been fighting cancer since first being diagnosed in 1999. After finding out about the new trial on the internet he applied and, after interviews, was accepted along with 16 other candidates. The treatment removed Origer’s melanoma and also shrunk another tumor in his liver – to the extent it could be removed surgically. Doctors confirmed he was free of the disease last week, nearly 2 years after treatment began. A second man (39) was cleared of his cancer which had spread to the lungs, liver and lymph nodes. Cancer that progresses to the lymph nodes is usually untreatable and fatal.

T cells can attack and destroy bacteria and other harmful cells like cancer cells. However cancer cells sometimes reduce the signals on their outer surface by which they are recognised, so the immune system cannot affect them. Gene therapy involves modifying some of a patients T cells to contain a new receptor. (Receptors are what enable the immune cell to identify harmful cells, like those corrupted by viruses. The new receptor is inserted with the use of a viral vector, i.e. a virus made safe to insert the receptor in the cell.

In the trial, T Cells were removed from each patient and modified in the laboratory. Patients underwent chemotherapy to kill most of their current immune system, which was replaced by the mutated cells. The modified cells successfully survived after injection into the body – making up 10% of the subject’s T cell count during the first 2 months. The team is now looking for ways to enable the cells to survive longer and in greater numbers.

Experts have called this a significant technical advance but warn that more patients need testing and the technique refining before any conclusive results can be drawn. Dr Edel O’Toole, consultant dermatologist and British Skin Foundation spokesman, said: “I think that the success of this approach in two patients shows promise, however 15 patients did not respond to the treatment suggesting that further work is needed to optimise this approach for all patients, which could take many years.”

Rosenberg now hopes to run a new trial with possibly stronger gene therapy treatments, he is currently awaiting FDA approval.

Gene therapy was much hyped after it’s first successful application in so called “bubble boys” (patients with severe combined immunodeficiency). After follow-up, these trials were stopped when it was discovered that three of eleven patients in one trial had developed leukemia.

Retrieved from “https://en.wikinews.org/w/index.php?title=Gene_therapy_trial_for_skin_cancer_cures_two_terminal_patients&oldid=717960”

Italy confirms swapping Taliban for Mastrogiacomo

Thursday, March 22, 2007

Italian journalist Daniele Mastrogiacomo who was held hostage for 15 days, was traded for five Taliban prisoners, as confirmed by Italian and Afgani authorities.

This likely represents the first time during the Iraq War or War in Afghanistan that prisoners were openly exchanged for a hostage. An Afghani government source said the swap “was an exceptional measure taken because we value our relations and friendship with Italy.”

Maybe the enemy will realize the great benefit they gained from this deal, and tomorrow even the reporters in Kabul won’t be safe. This is not good. The government can’t let the enemy use this strategy.

The move received sharp criticism from allies of Italy. In Washington, a senior State Department official said the United States was pleased the journalist had been released unharmed, but was troubled by possible ramifications of the swap. A spokesperson at the British Foreign Office said the deal sent “the wrong signal to prospective hostage-takers”.

Maxime Verhagen, Foreign Minister of the Netherlands spoke against the swap, “When we create situations where you can buy the freedom of Taliban fighters when you catch a journalist, in the short term there will be no journalists anymore.”

The international backlash is the latest headache for Italian Prime Minister Romano Prodi, who has fought hard to keep troops in Afghanistan despite resistance from pacifists within his centre-left coalition.

Prodi briefly resigned last month after a defeat in the Senate over his foreign policy, including Afghanistan, and needs the Senate next week to approve a refinancing of the mission.

An opinion poll published by Mastrogiacomo’s newspaper, La Repubblica, showed that 51 percent of Italians surveyed supported the exchange, while 41 percent opposed it.

Retrieved from “https://en.wikinews.org/w/index.php?title=Italy_confirms_swapping_Taliban_for_Mastrogiacomo&oldid=4500512”